Search results for: “abcg2”

CPIC® guideline for statins and SLCO1B1, ABCG2, and CYP2C9 For gene-specific information tables (i.e. ABCG2 allele definition, allele functionality, and frequency tables) see guideline pages or PharmGKB.

Most recent guideline publication: The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1, ABCG2, and CYP2C9 and statin-associated musculoskeletal symptoms (January 2022) Updates since publication: none Tables provided in the main manuscript of the guideline: Table 1. Assignment of predicted SLCO1B1, ABCG2, and CYP2C9 likely phenotype based on genotype Table 2. Dosing recommendations for statins…

Prioritizing the order of writing guidelines for CPIC genes/drugs is based on the following criteria: CPIC guidelines published, in progress, or planned Gene – Drug Current CPIC level* Status TPMT, NUDT15 – thiopurines A Published; update in progress CYP2C19 – clopidogrel A Published CYP2C9,VKORC1, CYP4F2 – warfarin A Published CYP2D6 – opioids A Published HLA-B…

What is CPIC? The Clinical Pharmacogenetics Implementation Consortium (CPIC®) is an international consortium of individual volunteers and a small dedicated staff who are interested in facilitating use of pharmacogenetic tests for patient care.One barrier to implementation of pharmacogenetic testing in the clinic is the difficulty in translating genetic laboratory test results into actionable prescribing decisions for…