Search results for: “interferon”

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG interferon-alpha-based Regimens (February 2014) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1 Assignment of probable IFNL3 phenotypes based on genotypes Table 2 Recommendations for use of…

CPIC guideline for PEG interferon-alpha-based regimens based on IFNL3/4 genotype   For gene-specific information tables (i.e. IFNL3/4 allele definition and gene resource mappings tables) see guideline page or PharmGKB.

Prioritizing the order of writing guidelines for CPIC genes/drugs is based on the following criteria: CPIC guidelines published, in progress, or planned Gene – Drug Current CPIC level* Status TPMT, NUDT15 – thiopurines A Published; update in progress CYP2C19 – clopidogrel A Published CYP2C9,VKORC1, CYP4F2 – warfarin A Published CYP2D6 – opioids A Published HLA-B…