CPIC® Guideline for PEG Interferon-Alpha-Based Regimens and IFNL3

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG interferon-alpha-based Regimens (February 2014) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1 Assignment of probable IFNL3 phenotypes based on genotypes Table 2 Recommendations for use of […]

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Prioritization of CPIC Guidelines

Prioritizing the order of writing guidelines for CPIC genes/drugs is based on the following criteria: Is there prescribing actionability? What is the severity of the clinical consequences (adverse effects, lack of response) if genetics are not used to inform prescribing? Is the gene already subject to other CPIC guidelines? Is there an available genetic test […]

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