Most recent guideline publication:
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy (July 2024)
Updates since publication:
No updates on dosing recommendations since publication.
Tables and figure provided in the main manuscript of the guideline:
| Table 1. Assignment of likely CYP2B6 phenotypes based on genotype |
| Table 2. Methadone dosing recommendations based on CYP2B6 phenotype |
Supplement to: Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy (July 2024)
Tables and figures provided in the supplement or referenced in the guidelinea:
| Table S1. Evidence linking CYP2B6 to methadone phenotype |
| Figure S1. The challenges with CYP2B |
| CYP2B6 allele definition table |
| CYP2B6 allele functionality table |
| CYP2B6 frequency table |
| CYP2B6 diplotype-phenotype table |
| CYP2B6 gene resource mappings |
| Clinical Decision Support:b Not included because this guideline is a CPIC level C guideline (no recommendation) |