CPIC guideline for thiopurines based on TPMT and NUDT15 gentoype For gene-specific information tables (i.e. NUDT15 allele definition, allele functionality, frequency and diplotype-phenotype tables) see guideline pages or PharmGKB.
CPIC guideline for tacolimus based on CYP3A5 genotype For gene-specific information tables (i.e. CYP3A5 allele definition, allele functionality, and frequency tables) see guideline pages or PharmGKB.
Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype and Tacrolimus Dosing (July 2015) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of likely metabolism phenotypes based on CYP3A5 diplotypes Table 2. Dosing recommendations for tacrolimus based […]
Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium Guidelines for thiopurine dosing based on TPMT and NUDT15 genotypes: 2018 Update (November 2018) Updates since publication: April 2020: The authors of this guideline have added recommendations for TPMT and NUDT15 indeterminate phenotypes (i.e. combination of uncertain and/or unknown function alleles). TPMT indeterminate: Consider evaluating TPMT erythrocyte […]
CPIC in person meeting survey resutls cpic minutes nov 2015 CPIC Term Standardization and LOINC 151203 DIGITizE Overview Hicks presentation minutes cpic Apr 2015 minutes cpic August 2015 minutes cpic February 2015 minutes cpic Jan 2015 minutes cpic July 2015 minutes cpic june 2015 minutes cpic Mar 2015 minutes cpic May 2015 minutes cpic Oct […]
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Working group documents/information (posted as needed): Link to sign-up to be a clinical champion: https://forms.gle/SRQBQjApyCDrxKEv8 Working group minutes: 2020 May June September
CPIC guideline for thiopurines based on TPMT and NUDT15 gentoype For gene-specific information tables (i.e. TPMT allele definition, allele functionality, frequency and diplotype-phenotype tables) see guideline pages or PharmGKB.
February 2020 Meeting slides March 2020 May 2020 Pratt slides June 2020 July 2020 Gaedigk slides July 2020 August 2020 September 2020 Thomas slides Whirl-Carrillo slides October 2020 Grillo and Schuck slides
Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing (August 2020) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of predicted CYP2C19 phenotype based on genotype Table 2. Dosing recommendations for omeprazole, lansoprazole, […]