Search results for: “1 5”

February 2019 CYP2C19-Proton Pump Inhibitors Oslin slides March 2019 CPIC Twitter 101 Monte slides April 2019 Giacomini slides May 2019 Hoshitsuki slides Bousman/Mueller slides August 2019 FDA/PGx slides September 2019 Allele function assignment SOP and CYP2C9 function assignment CYP2C9 Genotyping Recommendations: AMP Pharmacogenomics Working Group AMP Clinical Practice Committee October 2019 CPIC update slides Relling…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for the use of potent volatile anesthetic agents and succinylcholine in the context of RYR1 or CACNA1S genotypes Updates since publication: December 2023: Subsequent to the publication of the CPIC guideline for RYR1 and malignant hyperthermia (PMID 30499100), the ClinGen variant curation expert panel (VCEP) developed and published…

February 2018 Thomas slides March 2018 Peterson slides Gregornik slides April 2018 Pulk slides Pratt slides May 2018 Caudle slides June 2018 Newman slides August 2018 2018 ASCO Endorsement Methods September 2018 CYP2D6 genotype to phenotype standardization project slides October 2018 November 2018 Huddart slides December 2018 Database/API slides

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Voriconazole Therapy (December 2016) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of likely CYP2C19 phenotype based on genotypes Table 2. Dosing recommendations for voriconazole based on CYP2C19…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 update (January 2022) Updates since publication: None Tables in the main manuscript of the guideline: Table 1. Assignment of Predicted CYP2C19 Phenotype Based on Genotype Table 2. Antiplatelet therapy recommendations based on CYP2C19 phenotype when considering clopidogrel for cardiovascular…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype and Tacrolimus Dosing (July 2015) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of likely metabolism phenotypes based on CYP3A5 diplotypes Table 2. Dosing recommendations for tacrolimus based…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6, OPRM1, and COMT genotype and select opioid therapy (December 2020) Tables and figure provided in the main manuscript of the guideline: Table 1. Assignment of predicted CYP2D6 phenotypes based on diplotypes Table 2. Codeine therapy recommendations based on CYP2D6 phenotype Table 3. Tramadol…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors (August 2015) Updates since publication: October 2019: CYP2D6 genotype to phenotype translation changes: Up until August 2019, there were a few inconsistencies in the translation of CYP2D6 genotype to phenotype across guidelines (i.e.…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for UGT1A1 and Atazanavir Prescribing (September 2015) Updates since publication: November 2017: UGT1A1*80 is in very high linkage disequilibrium with *28 and *37. In the rare event that *80 is detected but *28 and *37 are not, there are not enough clinical data to predict…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC®) for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants: 2016 Update (December 2016) Updates since publication: October 2019: CYP2D6 genotype to phenotype translation changes: Up until August 2019, there were a few inconsistencies in the translation of CYP2D6 genotype to phenotype across guidelines (i.e.…