CPIC

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  • CPIC® Guideline for Methadone based on CYP2B6 genotype

    This guideline is in progress.

  • 2023 CPIC Conference Call Minutes

    January Voora slides February Hertz slides Surprenant slides March CPIC update April May El Rouby slides June Saulsberry slides August Pratt slides Newman slides September October Tuteja slides December Caudle slides Phillips slides FDA response to codeine citizen petition

  • CPIC® Guideline for Serotonin Reuptake Inhibitor Antidepressants and CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A

    Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants (April 2023) Updates since publication: None Tables provided in the main manuscript of the guideline: Table 1. Assignment of predicted phenotypes based on diplotypes Table 2. Dosing recommendations for antidepressants based on…

  • CPIC® Guideline for Beta-blockers and CYP2D6, ADRB1, ADRB2, GRK4, and GRK5

    This guideline is in progress

  • CPIC® guideline for statins and SLCO1B1, ABCG2, and CYP2C9

    Most recent guideline publication: The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1, ABCG2, and CYP2C9 and statin-associated musculoskeletal symptoms (January 2022) Updates since publication: none Tables provided in the main manuscript of the guideline: Table 1. Assignment of predicted SLCO1B1, ABCG2, and CYP2C9 likely phenotype based on genotype Table 2. Dosing recommendations for statins…

  • 2022 CPIC Conference Call Minutes

    February 2022 Gaedigk slides Right Drug Dose Now Act March 2022 April 2022 Relling slides June 2022 Pirmohamed slides July 2022 October 2022 November 2022

  • CPIC® Guideline for G6PD

    Guideline overview presentation Most recent guideline publication: Expanded Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Medication Use in the Context of G6PD Genotype (August 2022) Tables  provided in the main manuscript of the guideline: Table 1. Assignment of predicted G6PD phenotype based on genotype Table 2. Drug-specific risk level and associated strength of recommendation for…

  • MT-RNR1 CPIC Guidelines

    CPIC guideline for aminoglycosides based on MT-RNR1 genotype   For gene-specific information tables (i.e. MT-RNR1 allele definition, allele functionality, and frequency tables) see guideline pages or PharmGKB.

  • CPIC Communication

    There are a few different ways to stay in touch with CPIC. I have a question or comments Contact us with any questions or comments. I have a question or comment about allele function or diplotype-phenotype tables Contact us with questions specifically about CPIC alleles I want to get announcements CPIC has a public announcement…

  • About Us

    Kelly E. Caudle, PharmD, PhD, BCPS, FCCP CPIC Co-PI/Director, Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN Dr. Caudle received her Pharm.D. and Ph.D. from The University of Tennessee Health Science Center and completed an ASHP-accredited PGY2 residency at Le Bonheur Children’s Hospital in Memphis, TN. She is also a board‐certified Pharmacotherapy…