Search results for: “excel”

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Voriconazole Therapy (December 2016) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of likely CYP2C19 phenotype based on genotypes Table 2. Dosing recommendations for voriconazole based on CYP2C19…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C9 and HLA-B Genotype and Phenytoin Dosing (August 2020) Updates since publication: No updates on dosing recommendations since publication. Tables and figure provided in the main manuscript of the guideline: Table 1. Assignment of likely HLA-B phenotypes based on genotypes Table 2. Assignment of…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 update (January 2022) Updates since publication: None Tables in the main manuscript of the guideline: Table 1. Assignment of Predicted CYP2C19 Phenotype Based on Genotype Table 2. Antiplatelet therapy recommendations based on CYP2C19 phenotype when considering clopidogrel for cardiovascular…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Pharmacogenetics-guided Warfarin Dosing: 2016 Update (December 2016) Updates since publication: No updates on dosing recommendations since this publication. Figures provided in the main manuscript of the guideline: Figure 1. Schematic representation of warfarin metabolism and its mechanism of action. Figure 2. Dosing recommendations for…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype and Tacrolimus Dosing (July 2015) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of likely metabolism phenotypes based on CYP3A5 diplotypes Table 2. Dosing recommendations for tacrolimus based…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Ivacaftor Therapy in the Context of CFTR Genotype (March 2014) Updates since publication: May 2019: The FDA-approved drug label for ivacaftor has been updated to include additional variants, bringing the total number of indicated variants to 38. The CPIC guideline supplement and CFTR Allele…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6, OPRM1, and COMT genotype and select opioid therapy (December 2020) Tables and figure provided in the main manuscript of the guideline: Table 1. Assignment of predicted CYP2D6 phenotypes based on diplotypes Table 2. Codeine therapy recommendations based on CYP2D6 phenotype Table 3. Tramadol…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors (August 2015) Updates since publication: October 2019: CYP2D6 genotype to phenotype translation changes: Up until August 2019, there were a few inconsistencies in the translation of CYP2D6 genotype to phenotype across guidelines (i.e.…

  Most recent guideline publication Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update (December 2017) Updates since publication: No updates on dosing recommendations since publication. Tables provided in the main manuscript of the guideline: Table 1. Assignment of HLA-B and HLA-A genotypes Table 2. Recommendations for…

Most recent guideline publication: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update (October 2017) Updates since publication: January 2024 update (edited March 2024): Recently, individual patients have been reported (PMID 38129972) to carry only one of the two SNPs in the HapB3 haplotype (i.e., c.1236G>A without c.1129-5923C>G), suggesting…